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Defective sumoylation pathway directs congenital heart disease

Congenital heart defects (CHDs) are the most common of all birth defects, yet molecular mechanism(s) underlying highly prevalent atrial septal defects (ASDs) and ventricular septal defects (VSDs) have remained elusive. We demonstrate the indispensability of “balanced” post-translational SUMO conjuga...

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Publicat a:Birth Defects Res A Clin Mol Teratol
Autors principals: Wang, Jun, Chen, Li, Wen, Shu, Zhu, Huiping, Yu, Wei, Moskowitz, Ivan P., Shaw, Gary M., Finnell, Richard H., Schwartz, Robert J
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031480/
https://ncbi.nlm.nih.gov/pubmed/21563299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20816
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