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Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL‐17 responses

The Th17/IL‐17 pathway is implicated in the pathogenesis of periodontitis (PD), however the mechanisms are not fully understood. We investigated the mechanism by which the periodontal pathogens Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) promote a Th17/IL‐17 response...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Cheng, Wan‐Chien, van Asten, Saskia D., Burns, Lachrissa A., Evans, Hayley G., Walter, Gina J., Hashim, Ahmed, Hughes, Francis J., Taams, Leonie S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031191/
https://ncbi.nlm.nih.gov/pubmed/27334899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545871
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