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Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomal MicroRNAs Suppress Myofibroblast Differentiation by Inhibiting the Transforming Growth Factor-β/SMAD2 Pathway During Wound Healing

Excessive scar formation caused by myofibroblast aggregations is of great clinical importance during skin wound healing. Studies have shown that mesenchymal stem cells (MSCs) can promote skin regeneration, but whether MSCs contribute to scar formation remains undefined. We found that umbilical cord-...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Fang, Shuo, Xu, Chen, Zhang, Yuntong, Xue, Chunyu, Yang, Chao, Bi, Hongda, Qian, Xijing, Wu, Minjuan, Ji, Kaihong, Zhao, Yunpeng, Wang, Yue, Liu, Houqi, Xing, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031180/
https://ncbi.nlm.nih.gov/pubmed/27388239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0367
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