Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomal MicroRNAs Suppress Myofibroblast Differentiation by Inhibiting the Transforming Growth Factor-β/SMAD2 Pathway During Wound Healing

Excessive scar formation caused by myofibroblast aggregations is of great clinical importance during skin wound healing. Studies have shown that mesenchymal stem cells (MSCs) can promote skin regeneration, but whether MSCs contribute to scar formation remains undefined. We found that umbilical cord-...

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Vydáno v:Stem Cells Transl Med
Hlavní autoři: Fang, Shuo, Xu, Chen, Zhang, Yuntong, Xue, Chunyu, Yang, Chao, Bi, Hongda, Qian, Xijing, Wu, Minjuan, Ji, Kaihong, Zhao, Yunpeng, Wang, Yue, Liu, Houqi, Xing, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2016
Témata:
Tissue Engineering and Regenerative Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031180/
https://ncbi.nlm.nih.gov/pubmed/27388239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0367
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