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Translesion Synthesis of the N(2)-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1
[Image: see text] Translesion synthesis (TLS) of the N(2)-2′-deoxyguanosine (dG-N(2)-IQ) adduct of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) was investigated in human embryonic kidney 293T cells by replicating plasmid constructs in which the adduct was individually placed at each g...
Gespeichert in:
| Veröffentlicht in: | Chem Res Toxicol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2016
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031085/ https://ncbi.nlm.nih.gov/pubmed/27490094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00221 |
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