Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney

Cardiovascular and renal pathologies are frequently associated with an activated renin-angiotensin-system (RAS) and increased levels of its main effector and vasoconstrictor hormone angiotensin II (Ang II). Angiotensin-converting-enzyme-2 (ACE2) has been described as a crucial enzymatic player in sh...

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Pubblicato in:Sci Rep
Autori principali: Domenig, Oliver, Manzel, Arndt, Grobe, Nadja, Königshausen, Eva, Kaltenecker, Christopher C., Kovarik, Johannes J., Stegbauer, Johannes, Gurley, Susan B., van Oyen, Dunja, Antlanger, Marlies, Bader, Michael, Motta-Santos, Daisy, Santos, Robson A., Elased, Khalid M., Säemann, Marcus D., Linker, Ralf A., Poglitsch, Marko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030486/
https://ncbi.nlm.nih.gov/pubmed/27649628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33678
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