A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

We wanted to examine tolerability and efficacy of NSI-189, a benzylpiperizine-aminiopyridine neurogenic compound for treating major depressive disorder (MDD). This was a Phase 1B, double blind, randomized, placebo controlled, multiple-dose study with three cohorts. The first cohort received 40 mg q....

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Dettagli Bibliografici
Pubblicato in:Mol Psychiatry
Autori principali: Fava, M, Johe, K, Ereshefsky, L, Gertsik, L G, English, B A, Bilello, J A, Thurmond, L M, Johnstone, J, Dickerson, B C, Makris, N, Hoeppner, B B, Flynn, M, Mischoulon, D, Kinrys, G, Freeman, M P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030464/
https://ncbi.nlm.nih.gov/pubmed/26643541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.178
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