NSI‐189, a small molecule with neurogenic properties, exerts behavioral, and neurostructural benefits in stroke rats

Enhancing neurogenesis may be a powerful stroke therapy. Here, we tested in a rat model of ischemic stroke the beneficial effects of NSI‐189, an orally active, new molecular entity (mol. wt. 366) with enhanced neurogenic activity, and indicated as an anti‐depressant drug in a clinical trial (Fava et...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Physiol
Prif Awduron: Tajiri, Naoki, Quach, David M., Kaneko, Yuji, Wu, Stephanie, Lee, David, Lam, Tina, Hayama, Ken L., Hazel, Thomas G., Johe, Karl, Wu, Michael C., Borlongan, Cesar V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Original Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518191/
https://ncbi.nlm.nih.gov/pubmed/28181668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25847
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