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Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

Colorectal cancer is the third most common cancer worldwide and is associated with significant morbidity and mortality. Current pharmacotherapy options include cytotoxic chemotherapy, anti-VEGF, and anti-EGFR targeting drugs, but these are limited by toxic side effects, limited responses and ultimat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Burke, Lorraine, Butler, Clare T., Murphy, Adrian, Moran, Bruce, Gallagher, William M., O'Sullivan, Jacintha, Kennedy, Breandán N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030284/
https://ncbi.nlm.nih.gov/pubmed/27709113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00103
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