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Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis

Mitochondrial DNA (mtDNA) depletion occurs frequently in many diseases including cancer. The present study was designed in order to examine the hypothesis that mtDNA-depleted cells are resistant to apoptosis and to explore the possible mechanisms responsible for this effect. Parental human osteosarc...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Chen, Hulin, Wang, Junling, Liu, Zhongrong, Yang, Huilan, Zhu, Yingjie, Zhao, Minling, Liu, Yan, Yan, Miaomiao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029958/
https://ncbi.nlm.nih.gov/pubmed/27499009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2697
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