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Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells

Pulmonary fibrosis is a devastating, incurable disease in which chronic inflammation and dysregulated, excessive wound healing lead to progressive fibrosis, lung dysfunction, and ultimately death. Prior studies have implicated the cytokine IL-17A and Th17 cells in promoting the development of fibros...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vigeland, Christine L., Collins, Samuel L., Chan-Li, Yee, Hughes, Andrew H., Oh, Min-Hee, Powell, Jonathan D., Horton, Maureen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029914/
https://ncbi.nlm.nih.gov/pubmed/27649073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163288
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