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Increased taurine in pre-weaned juvenile mdx mice greatly reduces the acute onset of myofibre necrosis and dystropathology and prevents inflammation

Background: The mdx mouse model for the fatal muscle wasting disease Duchenne Muscular Dystrophy (DMD) shows a very mild pathology once growth has ceased, with low levels of myofibre necrosis in adults. However, from about 3 weeks of post-natal age, muscles of juvenile mdx mice undergo an acute bout...

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Bibliografiska uppgifter
I publikationen:PLoS Curr
Huvudupphovsmän: Terrill, Jessica R., Grounds, Miranda D, Arthur, Peter G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029885/
https://ncbi.nlm.nih.gov/pubmed/27679740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.md.77be6ec30e8caf19529a00417614a072
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