Increasing taurine intake and taurine synthesis improves skeletal muscle function in the mdx mouse model for Duchenne muscular dystrophy

KEY POINTS: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease associated with increased inflammation, oxidative stress and myofibre necrosis. Cysteine precursor antioxidants such as N‐acetyl cysteine (NAC) and l‐2‐oxothiazolidine‐4‐carboxylate (OTC) reduce dystropathology in the md...

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Bibliographic Details
Published in:J Physiol
Main Authors: Terrill, Jessica R., Pinniger, Gavin J., Graves, Jamie A., Grounds, Miranda D., Arthur, Peter G.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Muscle
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887673/
https://ncbi.nlm.nih.gov/pubmed/26659826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271418
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