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Signaling Modification by GPCR Heteromer and Its Implication on X-Linked Nephrogenic Diabetes Insipidus

The involvement of secretin (SCT) and secretin receptor (SCTR) in regulating body water homeostasis is well established. Identified as one of the vasopressin (Vp)-independent mechanisms in fluid balance, SCT regulates aquaporin 2 (AQP2) in the kidney distal collecting duct cells through activating i...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Ng, Hans K. H., Harikumar, Kaleeckal G., Miller, Laurence J., Chow, Billy K. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029868/
https://ncbi.nlm.nih.gov/pubmed/27649563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163086
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