Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex

Angiotensin (ANGII) and secretin (SCT) share overlapping, interdependent osmoregulatory functions in brain, where SCT peptide/receptor function is required for ANGII action, yet the molecular basis is unknown. Since receptors for these peptides (AT1aR, SCTR) are coexpressed in osmoregulatory centers...

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Detalhes bibliográficos
Main Authors: Lee, Leo T. O., Ng, Stephanie Y. L., Chu, Jessica Y. S., Sekar, Revathi, Harikumar, Kaleeckal G., Miller, Laurence J., Chow, Billy K. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021437/
https://ncbi.nlm.nih.gov/pubmed/24599969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-246868
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