Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative

Background: Identification of clinically relevant oncogenic drivers in advanced cancer is critical in selecting appropriate targeted therapy. Using next-generation sequencing (NGS)-based clinical cancer gene assay, we performed comprehensive genomic profiling (CGP) of advanced cases of lung adenocar...

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Udgivet i:Oncotarget
Main Authors: Lim, Sun Min, Kim, Eun Young, Kim, Hye Ryun, Ali, Siraj M., Greenbowe, Joel R., Shim, Hyo Sup, Chang, Hyun, Lim, Seungtaek, Paik, Soonmyung, Cho, Byoung Chul
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029692/
https://ncbi.nlm.nih.gov/pubmed/26992220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8138
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