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Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts

Cell line-derived xenografts (CDXs) are an integral part of drug efficacy testing during development of new pharmaceuticals against cancer but their accuracy in predicting clinical responses in patients have been debated. Patient-derived xenografts (PDXs) are thought to be more useful for predictive...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Bhadury, Joydeep, Einarsdottir, Berglind O., Podraza, Agnieszka, Bagge, Roger Olofsson, Stierner, Ulrika, Ny, Lars, López, Marcela Dávila, Nilsson, Jonas A.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029664/
https://ncbi.nlm.nih.gov/pubmed/27009863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8181
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