Increased chemoresistance via Snail–Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative

A tobacco-specific component, 4-methylnitrosamino-1-3-pyridyl-1-butanone (NNK), is a major risk factor for many cancers. Recent reports have demonstrated that NNK exposure may be associated with tumor progression and chemoresistance in certain cancers. However, the underlying NNK-induced mechanism c...

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Publicado en:Oncotarget
Autores principales: Lee, Tsai-Yu, Liu, Chia-Lin, Chang, Yun-Ching, Nieh, Shin, Lin, Yaoh-Shiang, Jao, Shu-Wen, Chen, Su-Feng, Liu, Tsung-Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029643/
https://ncbi.nlm.nih.gov/pubmed/26992205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8049
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