Adipose triglyceride lipase decrement affects skeletal muscle homeostasis during aging through FAs-PPARα-PGC-1α antioxidant response

During aging skeletal muscle shows an accumulation of oxidative damage as well as intramyocellular lipid droplets (IMLDs). However, although the impact of these modifications on muscle tissue physiology is well established, the direct effectors critical for their occurrence are poorly understood. He...

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Vydáno v:Oncotarget
Hlavní autoři: Aquilano, Katia, Baldelli, Sara, Barbera, Livia La, Barbato, Daniele Lettieri, Tatulli, Giuseppe, Ciriolo, Maria Rosa
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Gerotarget (Focus on Aging)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029607/
https://ncbi.nlm.nih.gov/pubmed/27056902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8552
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