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Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration

Mitochondrial activity progressively declines during ageing and in many neurodegenerative diseases. Caloric restriction (CR) has been suggested as a dietary intervention that is able to postpone the detrimental aspects of aging as it ameliorates mitochondrial performance. This effect is partially du...

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Detalhes bibliográficos
Main Authors: Lettieri Barbato, Daniele, Baldelli, Sara, Pagliei, Beatrice, Aquilano, Katia, Ciriolo, Maria Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399559/
https://ncbi.nlm.nih.gov/pubmed/22829833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/759583
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