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Molecularly Severe roX1 Mutations Contribute to Dosage Compensation in Drosophila

Drosophila melanogaster males maintain a constant ratio of X-linked to autosomal gene products by increasing expression from their single X chromosome. This is achieved through the action of a complex composed of protein and roX RNA. This complex binds in the body of genes and increases expression t...

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Bibliographic Details
Published in:Genesis
Main Authors: Deng, Xinxian, Meller, Victoria H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029428/
https://ncbi.nlm.nih.gov/pubmed/19101984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20463
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