Tandem Stem Loops in roX RNAs Act Together to Mediate X Chromosome Dosage Compensation in Drosophila

Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding RNAs (lncRNAs) for transcriptional upregulation of the male X chromosome. Here, by using UV crosslinking followed by deep sequencing, we show that two enzymes in the Male-Specific Lethal complex, MLE...

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Detalhes bibliográficos
Main Authors: Ilik, Ibrahim Avsar, Quinn, Jeffrey J., Georgiev, Plamen, Tavares-Cadete, Filipe, Maticzka, Daniel, Toscano, Sarah, Wan, Yue, Spitale, Robert C., Luscombe, Nicholas, Backofen, Rolf, Chang, Howard Y., Akhtar, Asifa
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804161/
https://ncbi.nlm.nih.gov/pubmed/23870142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.001
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