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The effects of cytotoxic necrotizing factor 1 expression in the uptake of Escherichia coli K1 by macrophages and the onset of meningitis in newborn mice

Macrophages are a permissive niche for E. coli K1 multiplication for which the interaction of the bacterial outer membrane protein A and its cognate receptor CD64 are critical. Using in vitro immunofluorescence and live microscopy with ex vivo macrophage cultures from RFP-Lifeact mice, we show that...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Chang, Alexander C., Krishnan, Subramanian, Prasadarao, Nemani V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029305/
https://ncbi.nlm.nih.gov/pubmed/27221788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2016.1192730
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