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Nucleosome distortion as a possible mechanism of transcription activation domain function

After more than three decades since the discovery of transcription activation domains (ADs) in gene-specific activators, the mechanism of their function remains enigmatic. The widely accepted model of direct recruitment by ADs of co-activators and basal transcriptional machinery components, however,...

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Bibliografische gegevens
Gepubliceerd in:Epigenetics Chromatin
Hoofdauteurs: Erkina, Tamara Y., Erkine, Alexandre M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029090/
https://ncbi.nlm.nih.gov/pubmed/27679670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0092-2
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