WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines

BACKGROUND: Invasive lobular carcinoma (ILC) of the breast typically presents with clinical biomarkers consistent with a favorable response to endocrine therapies, and over 90 % of ILC cases express the estrogen receptor (ER). However, a subset of ILC cases may be resistant to endocrine therapies, s...

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Pubblicato in:Breast Cancer Res
Autori principali: Sikora, Matthew J., Jacobsen, Britta M., Levine, Kevin, Chen, Jian, Davidson, Nancy E., Lee, Adrian V., Alexander, Caroline M., Oesterreich, Steffi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028957/
https://ncbi.nlm.nih.gov/pubmed/27650553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0748-7
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