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Enhanced release of primary signals may render intercellular signalling ineffective due to spatial aspects

Detailed mechanistic modelling has been performed of the intercellular signalling cascade between precancerous cells and their normal neighbours that leads to a selective removal of the precancerous cells by apoptosis. Two interconnected signalling pathways that were identified experimentally have b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kundrát, Pavel, Friedland, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028836/
https://ncbi.nlm.nih.gov/pubmed/27645799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33214
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