Bcl-2 homologue Debcl enhances α-synuclein-induced phenotypes in Drosophila

BACKGROUND: Parkinson disease (PD) is a debilitating movement disorder that afflicts 1–2% of the population over 50 years of age. The common hallmark for both sporadic and familial forms of PD is mitochondrial dysfunction. Mammals have at least twenty proapoptotic and antiapoptotic Bcl-2 family memb...

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Bibliographic Details
Published in:PeerJ
Main Authors: M’Angale, P. Githure, Staveley, Brian E.
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028777/
https://ncbi.nlm.nih.gov/pubmed/27672511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2461
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