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The Bcl-2 homologue Buffy rescues α-synuclein-induced Parkinson disease-like phenotypes in Drosophila

BACKGROUND: In contrast to the complexity found in mammals, only two Bcl-2 family genes have been found in Drosophila melanogaster including the pro-cell survival, human Bok-related orthologue, Buffy. The directed expression of α-synuclein, the first gene identified to contribute to inherited forms...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: M’Angale, P. Githure, Staveley, Brian E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872331/
https://ncbi.nlm.nih.gov/pubmed/27192974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0261-z
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