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Modulation of Phenotype and Function of Human CD4(+)CD25(+) T Regulatory Lymphocytes Mediated by cAMP-Elevating Agents
We have shown that cholera toxin (CT) and other cyclic AMP (cAMP)-elevating agents induce upregulation of the inhibitory molecule CTLA-4 in human resting CD4(+) T lymphocytes, which following the treatment acquired suppressive functions. In this study, we evaluated the effect of cAMP-elevating agent...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028705/ https://ncbi.nlm.nih.gov/pubmed/27703455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00358 |
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