A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis

BACKGROUND: Almost without exception, patients with heparin-induced thrombocytopenia/thrombosis (HIT) have antibodies that recognize platelet factor 4 (PF4) in a complex with heparin; however, many heparin-treated patients without HIT are also antibody-positive. A platelet activation test, the serot...

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Udgivet i:Chest
Main Authors: Padmanabhan, Anand, Jones, Curtis G., Curtis, Brian R., Bougie, Daniel W., Sullivan, Mia J., Peswani, Namrata, McFarland, Janice G., Eastwood, Daniel, Wang, Demin, Aster, Richard H.
Format: Artigo
Sprog:Inglês
Udgivet: American College of Chest Physicians 2016
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Original Research: Critical Care
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028397/
https://ncbi.nlm.nih.gov/pubmed/26905366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chest.2016.02.641
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