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Francisella tularensis Live Vaccine Strain deficient in capB and overexpressing the fusion protein of IglA, IglB, and IglC from the bfr promoter induces improved protection against F. tularensis respiratory challenge

A safer and more effective vaccine than the unlicensed Francisella tularensis Live Vaccine Strain (LVS) is needed to protect against the biowarfare agent F. tularensis. Previously, we developed an LVS ΔcapB mutant that is significantly safer than LVS and provides potent protective immunity against F...

詳細記述

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書誌詳細
出版年:Vaccine
主要な著者: Jia, Qingmei, Bowen, Richard, Lee, Bai-Yu, Dillon, Barbara Jane, Masleša-Galić, Saša, Horwitz, Marcus A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028307/
https://ncbi.nlm.nih.gov/pubmed/27577555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.041
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