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Francisella tularensis Live Vaccine Strain deficient in capB and overexpressing the fusion protein of IglA, IglB, and IglC from the bfr promoter induces improved protection against F. tularensis respiratory challenge

A safer and more effective vaccine than the unlicensed Francisella tularensis Live Vaccine Strain (LVS) is needed to protect against the biowarfare agent F. tularensis. Previously, we developed an LVS ΔcapB mutant that is significantly safer than LVS and provides potent protective immunity against F...

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書目詳細資料
發表在:Vaccine
Main Authors: Jia, Qingmei, Bowen, Richard, Lee, Bai-Yu, Dillon, Barbara Jane, Masleša-Galić, Saša, Horwitz, Marcus A.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028307/
https://ncbi.nlm.nih.gov/pubmed/27577555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.041
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