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Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival

In solid tumours millions of cells are shed into the blood circulation each day. Only a subset of these circulating tumour cells (CTCs) survive, many of them presumable because of their potential to form multi-cellular clusters also named spheroids. Tumour cells within these spheroids are protected...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Braunholz, Diana, Saki, Mohammad, Niehr, Franziska, Öztürk, Merve, Borràs Puértolas, Berta, Konschak, Robert, Budach, Volker, Tinhofer, Ingeborg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028019/
https://ncbi.nlm.nih.gov/pubmed/27643613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163149
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