Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival

In solid tumours millions of cells are shed into the blood circulation each day. Only a subset of these circulating tumour cells (CTCs) survive, many of them presumable because of their potential to form multi-cellular clusters also named spheroids. Tumour cells within these spheroids are protected...

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Veröffentlicht in:PLoS One
Hauptverfasser: Braunholz, Diana, Saki, Mohammad, Niehr, Franziska, Öztürk, Merve, Borràs Puértolas, Berta, Konschak, Robert, Budach, Volker, Tinhofer, Ingeborg
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028019/
https://ncbi.nlm.nih.gov/pubmed/27643613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163149
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