Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease

Vascular dysfunction and decreased cerebral blood flow are linked to Alzheimer's disease (AD). Loss of endothelial nitric oxide (NO) and oxidative stress in human cerebrovascular endothelium increase expression of amyloid precursor protein (APP) and enhance production of the Aβ peptide, suggest...

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Foilsithe in:Physiol Rep
Main Authors: Roberts, Andrew M., Jagadapillai, Rekha, Vaishnav, Radhika A., Friedland, Robert P., Drinovac, Robert, Lin, Xingyu, Gozal, Evelyne
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027359/
https://ncbi.nlm.nih.gov/pubmed/27604401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12953
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