EPI-001, a compound active against castration-resistant prostate cancer, targets transactivation unit 5 of the androgen receptor

Castration-resistant prostate cancer is the lethal condition suffered by prostate cancer patients that become refractory to androgen deprivation therapy. EPI-001 is a recently identified compound active against this condition that modulates the activity of the androgen receptor, a nuclear receptor t...

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Udgivet i:ACS Chem Biol
Main Authors: De Mol, Eva, Fenwick, R. Bryn, Phang, Christopher T. W., Buzón, Victor, Szulc, Elzbieta, de la Fuente, Alex, Escobedo, Albert, García, Jesús, Bertoncini, Carlos W., Estébanez-Perpiñá, Eva, McEwan, Iain J., Riera, Antoni, Salvatella, Xavier
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027137/
https://ncbi.nlm.nih.gov/pubmed/27356095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00182
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