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GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion

GsMTx4 is a selective inhibitor of cationic mechanosensitive ion channels (MSCs) and has helped establish the role of MSCs in cardiac physiology. Inhomogeneous local mechanical stresses due to hypercontracture and swelling during ischemic reperfusion injury (IRI) likely induce elevated MSC activity...

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Détails bibliographiques
Publié dans:J Mol Cell Cardiol
Auteurs principaux: Wang, Jinli, Ma, Yina, Sachs, Frederick, Li, Ji, Suchyna, Thomas M.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026603/
https://ncbi.nlm.nih.gov/pubmed/27423272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.07.005
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