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GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion

GsMTx4 is a selective inhibitor of cationic mechanosensitive ion channels (MSCs) and has helped establish the role of MSCs in cardiac physiology. Inhomogeneous local mechanical stresses due to hypercontracture and swelling during ischemic reperfusion injury (IRI) likely induce elevated MSC activity...

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Bibliografiske detaljer
Udgivet i:J Mol Cell Cardiol
Main Authors: Wang, Jinli, Ma, Yina, Sachs, Frederick, Li, Ji, Suchyna, Thomas M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026603/
https://ncbi.nlm.nih.gov/pubmed/27423272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.07.005
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