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Kupffer Cell p38 MAPK Signaling Drives Post Burn Hepatic Damage and Pulmonary Inflammation when Alcohol Intoxication Precedes Burn Injury

OBJECTIVE: Clinical and animal studies demonstrate that alcohol intoxication at the time of injury worsens post-burn outcome. The purpose of this study was to determine the role and mechanism of Kupffer cell derangement in exacerbating post-burn end organ damage in alcohol exposed mice. DESIGN: Inte...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Chen, Michael M., O’Halloran, Eileen B., Ippolito, Jill A., Kovacs, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026536/
https://ncbi.nlm.nih.gov/pubmed/27322363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001817
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