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Kupffer Cell p38 MAPK Signaling Drives Post Burn Hepatic Damage and Pulmonary Inflammation when Alcohol Intoxication Precedes Burn Injury
OBJECTIVE: Clinical and animal studies demonstrate that alcohol intoxication at the time of injury worsens post-burn outcome. The purpose of this study was to determine the role and mechanism of Kupffer cell derangement in exacerbating post-burn end organ damage in alcohol exposed mice. DESIGN: Inte...
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| Veröffentlicht in: | Crit Care Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026536/ https://ncbi.nlm.nih.gov/pubmed/27322363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001817 |
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