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Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch are unclear. We showed recently that the unive...

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Detalles Bibliográficos
Publicado en:Sci Adv
Autores principales: Dubey, Badri N., Lori, Christian, Ozaki, Shogo, Fucile, Geoffrey, Plaza-Menacho, Ivan, Jenal, Urs, Schirmer, Tilman
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026420/
https://ncbi.nlm.nih.gov/pubmed/27652341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600823
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