Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease

BACKGROUND: Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood. The aim of this study was to identify a gene expression profile that is associated wi...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Duarte, Julio D., Desai, Ankit A., Sysol, Justin R., Abbasi, Taimur, Patel, Amit R., Lang, Roberto M., Gupta, Akash, Garcia, Joe G. N., Gordeuk, Victor R., Machado, Roberto F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026353/
https://ncbi.nlm.nih.gov/pubmed/27636371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163013
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