Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease

BACKGROUND: Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood. The aim of this study was to identify a gene expression profile that is associated wi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Duarte, Julio D., Desai, Ankit A., Sysol, Justin R., Abbasi, Taimur, Patel, Amit R., Lang, Roberto M., Gupta, Akash, Garcia, Joe G. N., Gordeuk, Victor R., Machado, Roberto F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026353/
https://ncbi.nlm.nih.gov/pubmed/27636371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163013
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