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Stop Codon Polymorphisms in the Human SLC9A1 Gene Disrupt or Compromise Na(+)/H(+) Exchanger Function
The NHE1 isoform of the mammalian Na(+)/H(+) exchanger is a ubiquitous plasma membrane protein that regulates intracellular pH in mammalian cells by removing one intracellular proton in exchange for one extracellular sodium. Deletion of the NHE1 gene (SLC9A1) affects the growth and motor ability of...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026351/ https://ncbi.nlm.nih.gov/pubmed/27636896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162902 |
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