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B-Raf Associates with and Activates the NHE1 Isoform of the Na(+)/H(+) Exchanger

The serine/threonine kinase B-Raf is the second most frequently occurring human oncogene after Ras. Mutations of B-Raf occur with the highest incidences in melanoma, and the most common mutant, V600E, renders B-Raf constitutively active. The sodium proton exchanger isoform 1 (NHE1) is a ubiquitously...

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Detalhes bibliográficos
Main Authors: Karki, Pratap, Li, Xiuju, Schrama, David, Fliegel, Larry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075656/
https://ncbi.nlm.nih.gov/pubmed/21345796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165134
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