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Treatment of multiple myeloma with the immunostimulatory SLAMF7 antibody elotuzumab

Elotuzumab is a humanized monoclonal antibody targeting the extracellular domain of signaling lymphocytic activation molecule F7 (SLAMF7) highly expressed in multiple myeloma cells. Upon binding to myeloma cells, elotuzumab exerts its cytotoxic effects through antibody-dependent cellular cytotoxicit...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Einsele, Hermann, Schreder, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026292/
https://ncbi.nlm.nih.gov/pubmed/27695618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620716657993
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