Three‐Dimensional Model of Human Nicotinamide Nucleotide Transhydrogenase (NNT) and Sequence‐Structure Analysis of its Disease‐Causing Variations

Defective mitochondrial proteins are emerging as major contributors to human disease. Nicotinamide nucleotide transhydrogenase (NNT), a widely expressed mitochondrial protein, has a crucial role in the defence against oxidative stress. NNT variations have recently been reported in patients with fami...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Metherell, Louise A, Guerra‐Assunção, José Afonso, Sternberg, Michael J, David, Alessia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026163/
https://ncbi.nlm.nih.gov/pubmed/27459240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23046
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