Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

Pattern recognition receptors detect microbial products and induce cytokines, which shape the immunological response. IL-12, TNF-α, and IL-1β are proinflammatory cytokines, which are essential for resistance against infection, but when produced at high levels they may contribute to immunopathology....

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Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Howes, Ashleigh, Taubert, Christina, Blankley, Simon, Spink, Natasha, Wu, Xuemei, Graham, Christine M., Zhao, Jiawen, Saraiva, Margarida, Ricciardi-Castagnoli, Paola, Bancroft, Gregory J., O’Garra, Anne
Format: Artigo
Langue:Inglês
Publié: AAI 2016
Sujets:
Innate Immunity and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026030/
https://ncbi.nlm.nih.gov/pubmed/27549173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501923
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