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LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells
Haematopoietic stem cells (HSCs) can differentiate into cells of all lineages in the blood. However, the mechanisms by which cytokines in the blood affect HSC homeostasis remain largely unknown. Here we show that leukocyte cell-derived chemotaxin 2 (LECT2), a multifunctional cytokine, induces HSC ex...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025878/ https://ncbi.nlm.nih.gov/pubmed/27596364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12719 |
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