ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Lipid accumulation in macrophages has profound effects on macrophage gene expression and contributes to the development of atherosclerosis. Here, we report that angiopoietin-like protein 4 (ANGPTL4) is the most highly upregulated gene in foamy macrophages and it's absence in haematopoietic cell...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Aryal, Binod, Rotllan, Noemi, Araldi, Elisa, Ramírez, Cristina M., He, Shun, Chousterman, Benjamin G., Fenn, Ashley M., Wanschel, Amarylis, Madrigal-Matute, Julio, Warrier, Nikhil, Martín-Ventura, Jose L., Swirski, Filip K., Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974469/
https://ncbi.nlm.nih.gov/pubmed/27460411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12313
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