ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Lipid accumulation in macrophages has profound effects on macrophage gene expression and contributes to the development of atherosclerosis. Here, we report that angiopoietin-like protein 4 (ANGPTL4) is the most highly upregulated gene in foamy macrophages and it's absence in haematopoietic cell...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Aryal, Binod, Rotllan, Noemi, Araldi, Elisa, Ramírez, Cristina M., He, Shun, Chousterman, Benjamin G., Fenn, Ashley M., Wanschel, Amarylis, Madrigal-Matute, Julio, Warrier, Nikhil, Martín-Ventura, Jose L., Swirski, Filip K., Suárez, Yajaira, Fernández-Hernando, Carlos
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974469/
https://ncbi.nlm.nih.gov/pubmed/27460411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12313
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